Germany on Thursday vowed stinging measures hitting tourism and investment in Turkey and a full "overhaul" of their troubled relations, signalling its patience had snapped after Ankara's arrests of human rights activists.
The government stepped up its travel advisory for the Nato ally as Foreign Minister Sigmar Gabriel warned it could no longer guarantee its citizens' safety in the face of "arbitrary" mass arrests, a step set to hit a sector crucial to Turkey's ailing economy.
A day after his ministry summoned Turkey's ambassador, Gabriel interrupted his holiday and returned to Berlin to deliver his unusually strong comments towards President Recep Tayyip Erdogan.
Relations between Turkey and Germany, home to three million ethnic Turks, have been badly strained, particularly since the failed coup a year ago against Erdogan.
Gabriel said Germany would review state guarantees for foreign investment in Turkey and urge businesses not to put their money there, and also reconsider its support for billions in EU financial flows earmarked over coming years for the long-time aspirant to membership of the bloc.
A Social Democrat, Gabriel made clear he was speaking for the coalition government led by conservative Chancellor Angela Merkel, and her spokesman soon tweeted that the steps were indeed "necessary and indispensable".
Gabriel recalled that Turkey, having long seen itself as "a member of the European family", had levelled Nazi jibes at Germany, and accused Erdogan of worsening a crisis that Berlin had repeatedly sought to ease through dialogue.
He accused Erdogan of trying to muzzle "every critical voice" with mass arrests in sweeping crackdowns over the last year.
Gabriel stressed that Germany still wanted to rebuild relations with its long-time ally but that first Erdogan's government must "return to European values".
Turkey's presidential spokesman Ibrahim Kalin accused Germany of "great political irresponsibility" in stepping up its travel warning and said: "We do not accept this."
He pointed to Germany's election in September, saying: "It's unacceptable to try and damage economic relations, try and arouse doubts in the minds of German investors, for the sake of petty electoral calculations."
Activists held 'hostage'  
A Turkish court on Tuesday ordered six rights activists to remain in custody for allegedly aiding a "terror" group -- among them Amnesty International's Turkey director Idil Eser and Berlin-based activist Peter Steudtner. 
Turkey in February arrested, on similar charges, German-Turkish journalist Deniz Yucel of Die Welt and is holding several other German citizens.
Erdogan has demanded Germany extradite people he blames for conspiring against him, mostly alleged followers of US-based Muslim cleric Fethullah Gulen whom he accuses of orchestrating the coup, a charge Gulen denies.
Germany has granted asylum to some Turkish dissidents, journalists and military officers who feared being swept up in the post-coup arrests.
German politicians and media have accused Erdogan of detaining German citizens as "hostages" to trade for Turks in Germany, but Gabriel said he "had heard of no official exchange offer".
News weekly Die Zeit said Ankara's blacklist also includes large German companies such as Daimler and BASF, claims dismissed as "absurd" by German security sources.
Gabriel, without referring to those claims, said that "you can't advise someone to invest in a country where there is no legal certainty and even completely innocent companies are linked to terrorism".
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