Three people, including two septuagenarians, died in Rautahat district while another three, including a two-year-old child, died in Saptari district on Saturday, they said.
Life has been severely affected by the cold waves that hit mainly southern Nepal districts over the past one week.
About 50 people have died of cold wave across the country this winter, with 27 of these deaths taking place in the southern Saptari district alone, the Kathmandu Post reported.
In a separate incident, five people were killed in a jeep accident in Sankhuwasabha district of eastern Nepal yesterday.
Makalu Rural Municipality chairperson Khadga Katuwal was among the deceased, according to chief district officer Shivaraj Joshi.
The accident took place at Samatar of Bhotkhola Rural Municipality in the district.
The ill-fated jeep en route to Dovan of Bhotkhola Rural Municipality from district headquarters Khandbari met with the accident at
around 12pm.
It is learnt that the jeep carried a team of staff belonging to National Reconstruction Authority. The reason for the accident is not known yet, the officials said.