Chinese scientists develop treatment for tendon-bone injuries

Chinese researchers conducted a study on the treatment of tendon-to-bone injuries, which concluded with the development of a treatment consisting of a multicellular scaffold based on inorganic bioceramics to treat these injuries.In this study, experts at the Shanghai Institute of Ceramics (SIC) of the Chinese Academy of Sciences addressed this problem through conducting a test on a group of animal models by integrating manganese silicate nanoparticles with tendon/bone-related cells, to construct an immunomodulatory multicellular scaffold to achieve integrated tendon-to-bone regeneration.The results showed that the scaffold developed and integrated not only demonstrated diverse biological activities in vitro, but also achieved immune regulation, multi-tissue integration regeneration and motor function recovery in a variety of animal models of rotator cuff injury.Wu Chengtie, a researcher at the institute and leader of the research, explained that the study provides a new concept for achieving immune modulation and integrated regeneration of tendons, bones and other tissue interfaces.The importance of this advanced treatment lies in the fact that restriction of motor activity due to loss of normal structure is a major cause of poor quality of life for patients suffering from tendon and bone injuries. Therefore, during this study, researchers hope that more treatments will be developed in the future to help treat these injuries.